Gamma Oryzanol

Studies Conducted On

Immunity boosting properties of Gamma-Oryzanol

Year of Study: 2017

Title of the Study: Gamma-Oryzanol-Rich Black Rice Bran Extract Enhances the Innate Immune Response / Soon Young Shin, Heon-Woong Kim, Hwan-Hee Jang, Yu-Jin Hwang, Jeong-Sook Choe, Yoongho Lim, Jung-Bong Kim, and Young Han Lee /Journal of Medicinal Food

This study showed that Gamma Oryzanol increases the expression of CD14 and Toll-like receptor 4 and enhances the phagocytic activity of RAW264.7 macrophages. Furthermore, Gamma Oryzanol promoted the secretion of innate cytokines, interleukin-8, and CCL2, which facilitate phagocytosis by RAW264.7 cells. These findings suggest that γ-oryzanol enhances innate immune responses.

Link: https://www.liebertpub.com/doi/pdf/10.1089/jmf.2017.3966

Year of Study: 2012

Title of the Study: Investigation of the immunomodulatory potential of oryzanol isolated from crude rice bran oil in experimental animal models. / Somsuvra B Ghatak, Shital J Panchal / Phytotherapy Research

The findings of this study indicate that Oryzanol possesses sufficient potential for augumenting immune activity by cellular and humoral mediated mechanisms

Link: https://www.ncbi.nlm.nih.gov/pubmed/22407738