Gamma Oryzanol

Studies Conducted On

Protective effects of Gamma Oryzanol on Kidneys

Year Of Study: 2021

Title Of The Study: Protective effects of Gamma Oryzanol on distant organs after kidney ischemia- reperfusion in rats: A focus on liver protection

Gamma Oryzanol protects distant organs against renal IRI-induced oxidative stress. Furthermore, it ameliorates liver function and remarkably exerts anti-oxidative, anti-inflammatory, and anti-apoptotic roles in the liver as an important detoxifying organ.

Link: https://pubmed.ncbi.nlm.nih.gov/33325270/

Year Of Study: 2021

Title Of The Study:  Low-Protein Diet: History and Use of Processed Low-Protein Rice for the Treatment of Chronic Kidney Disease

This study suggests that Dietary fibers and γ-oryzanol would stabilize intestinal microbiota and improve uremic dysbiosis and leaky gut syndrome. All these features suggest that the health benefits of LPBR extend to preventing CKD progression and enhancing the quality of life (QOL) of patients with Chronic Kidney Diseases (CKD).

Link: https://pubmed.ncbi.nlm.nih.gov/34681304/

Year Of Study: 2021

Title Of The Study: Gamma-oryzanol reduces renal inflammation and oxidative stress by modulating AGEs/RAGE axis in animals submitted to high sugar-fat diet

This study shows that gamma oryzanol is effective in reducing inflammation and oxidative stress in the kidney by modulating the AGEs/RAGE axis.

Link: https://pubmed.ncbi.nlm.nih.gov/34174064/

Year Of Study: 2021

Title Of The Study: Comparative study of gavage and intraperitoneal administration of gamma- oryzanol in alleviation/attenuation in a rat animal model of renal ischemia/reperfusion-induced injury

As per this study, a single dose of Gamma Oryzanol administration has a reno-protective effect against renal I/R injury. Gavage and IP administration exhibit similar efficiency in alleviation of I/R injury

Link: https://pubmed.ncbi.nlm.nih.gov/33953856/